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Dimitrios Kouretas 教授
2017-08-17 13:57   审核人:

    一、个人简介

    Dimitrios Kouretas,博士,希腊色萨利大学,生物化学生物技术、动物生理毒理学系教授。


    二、教育经历

希腊佩特雷大学 药学 学士学位(1985年)

希腊塞萨洛尼基大学 生物化学 博士学位(1989年)


    三、工作经历

1990-1992 哈佛大学医学院 博士后

1993-1995 希腊Theagenion癌症医院 研究员

1995 1997 希腊色萨利大学 讲师

1997 2003 希腊色萨利大学 助理教授

2003 2007 希腊色萨利大学 生物化学生物技术系 副教授

2007 至今 希腊色萨利大学 生物化学生物技术、动物生理毒理学系 教授


    四、研究方向

1.植物酚抗氧化活性的分子机制

2.氧化应激和运动

3.植物提取物的抗氧化活性

4.生物功能食品


    五、获得课题情况(近年来)

1.电子烟液的化学成分和毒性研究2012-2018年(和电子香烟公司合作 756000欧元)

2.患者氧化应激标志物和代谢谱研究2012-2018年(300000欧元)

3.基于螺旋藻的生物功能食品生物活性研究2014-2017年(20000欧元)

4.从圣山橄榄油中提取的橄榄油提取物的功能特性研究2016-2018年(50000欧元)

 

    六、发表文章情况(近年来)

1.Kouretas D, Tsatsakis AM, Domingo JL, Wallace Hayes A. Mechanisms involved in oxidative stress regulation. Food Chem Toxicol. 2013 61:1-2.

2.Sahpazidou D, Geromichalos GD, Stagos D, Apostolou A, Haroutounian SA, Tsatsakis AM, Tzanakakis GN, Hayes AW, Kouretas D. Anticarcinogenic activity of polyphenolic extracts from grape stems against breast, colon, renal and thyroid cancer cells. Toxicol Lett. 2014 (14)00062-9.

3.Kantsadi AL, Apostolou A, Theofanous S, Stravodimos GA, Kyriakis E, Gorgogietas VA, Chatzileontiadou DS, Pegiou K, Skamnaki VT, Stagos D, Kouretas D, Psarra AM, Haroutounian SA, Leonidas DD. Biochemical and biological assessment of the inhibitory potency of extracts from vinification byproducts of Vitis vinifera extracts against glycogen phosphorylase. Food Chem Toxicol. 2014 67:35-43.

4.Kerasioti E, Stagos D, Priftis A, Aivazidis S, Tsatsakis AM, Hayes AW, Kouretas D. Antioxidant effects of whey protein on muscle C2C12 cells. Food Chem. 2014 15;155:271-8.

5.Pechlivanis A, Chatziioannou AC, Veskoukis AS, Kouretas D, Mougios V, Theodoridis GA. GC-MS analysis of blood for the metabonomic investigation of the effects of physical exercise and allopurinol administration on rats. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 1;966:127-31.

6.Samaras A, Tsarouhas K, Paschalidis E, Giamouzis G, Triposkiadis F, Tsitsimpikou C, Becker AT, Goutzourelas N, Kouretas D. Effect of a special carbohydrate-protein bar and tomato juice supplementation on oxidative stress markers and vascular endothelial dynamics in ultra-marathon runners. Food Chem Toxicol. 2014 69:231-6.

7.Zafiropoulos A, Tsarouhas K, Tsitsimpikou C, Fragkiadaki P, Germanakis I, Tsardi M, Maravgakis G, Goutzourelas N, Vasilaki F, Kouretas D, Hayes A, Tsatsakis A. Cardiotoxicity in rabbits after a low-level exposure to diazinon, propoxur, and chlorpyrifos. Hum Exp Toxicol. 2014. [Epub ahead of print].

8.Manthou E, Kanaki M, Georgakouli K, Deli CK, Kouretas D, Koutedakis Y, Jamurtas AZ. Glycemic response of a carbohydrate-protein bar with ewe-goat whey. Nutrients. 2014 12;6(6):2240-50.

9.Matthaiou CM, Goutzourelas N, Stagos D, Sarafoglou E, Jamurtas A, Koulocheri SD, Haroutounian SA, Tsatsakis AM, Kouretas D. Pomegranate juice consumption increases GSH levels and reduces lipid and protein oxidation in human blood. Food Chem Toxicol. 2014 1;73C:1-6. [Epub ahead of print].

10.  Kolyva AS, Zolota V, Mpatsoulis D, Skroubis G, Solomou EE, Habeos IG, Assimakopoulos SF, Goutzourelas N, Kouretas D, Gogos CA. The role of obesity in the immune response during sepsis. Nutr Diabetes. 2014 4:e137.

11.  Goutzourelas N, Stagos D, Demertzis N, Mavridou P, Karterolioti H,Georgadakis S, Kerasioti E, Aligiannis N, Skaltsounis L, Statiri A, Tsioutsiouliti A, Tsatsakis AM, Hayes AW, Kouretas D. Effects of polyphenolic grape extract on the oxidative status of muscle and endothelial cells. Hum Exp Toxicol. 2014 33(11):1099-112.

12.Goutzourelas N, Stagos D, Housmekeridou A, Karapouliou C, Kerasioti E, Aligiannis N, Skaltsounis AL, Spandidos DA, Tsatsakis AM, Kouretas D. Grape pomace extract exerts antioxidant effects through an increase in GCS levels and GST activity in muscle and endothelial cells. Int J Mol Med. 2015 36(2):433-41.

13.  Margină D, Ilie M, Grădinaru D, Androutsopoulos VP, Kouretas D, Tsatsakis AM. Natural products-friends or foes? Toxicol Lett. 2015 Aug 5;236(3):154-67.

14.  Gerasopoulos K, Stagos D, Kokkas S, Petrotos K, Kantas D, Goulas P, Kouretas D. Feed supplemented with byproducts from olive oil mill wastewater processing increases antioxidant capacity in broiler chickens. Food Chem Toxicol. 2015 82:42-9.

15.  Stagos D, Goutzourelas N, Ntontou AM, Kafantaris I, Deli CK, Poulios A, Jamurtas AZ, Bar-Or D, Kouretas D. Assessment of eccentric exercise-induced oxidative stress using oxidation-reduction potential markers. Oxid Med Cell Longev. 2015;2015:204615.  

16.  Kavvalakis MP, Stivaktakis PD, Tzatzarakis MN, Kouretas D, Liesivuori J, Alegakis AK, Vynias D, Tsatsakis AM. Multicomponent analysis of replacement liquids of electronic cigarettes using chromatographic techniques. J Anal Toxicol. 2015 39(4):262-9.

17.  Stagos D, Apostolou A, Poulios E, Kermeliotou E, Mpatzilioti A, Kreatsouli K, Koulocheri SD, Haroutounian SA, Kouretas D. Antiangiogenic potential of grape stem extract through inhibition of vascular endothelial growth factor expression. J Physiol Pharmacol. 2014 65(6):843-52.

18.  Stagos D, Goutzourelas N, Bar-Or D, Ntontou AM, Bella E, Becker AT, Statiri A, Kafantaris I, Kouretas D. Application of a new oxidation-reduction potential assessment method in strenuous exercise-induced oxidative stress. Redox Rep. 2015 20(4):154-62.

19.  Kerksick CM, Tsatsakis AM, Hayes AW, Kafantaris I, Kouretas D. How can bioinformatics and toxicogenomics assist the next generation of research on physical exercise and athletic performance. J Strength Cond Res. 2015 29(1):270-8.

20.  Georgakouli, K., Manthou, E., Fatouros, I. G., Deli, C. K., Spandidos, D. A., Tsatsakis, A. M.,  Jamurtas, A. Z., Kouretas, D. Effects of acute exercise on liver function and blood redox status in heavy drinkers. Experimental and Therapeutic Medicine. 2015 10(6), 2015–2022.

21.  Gerasopoulos, K., Stagos, D., Kokkas, S., Petrotos, K., Kantas, D., Goulas, P., Kouretas, D. Feed supplemented with byproducts from olive oil mill wastewater processing increases antioxidant capacity in broiler chickens. Food and Chemical Toxicology : An International Journal Published for the British Industrial Biological Research Association. 2015, 82, 42–49.

22.  Gerasopoulos, K., Stagos, D., Petrotos, K., Kokkas, S., Kantas, D., Goulas, P., Kouretas, D. Feed supplemented with polyphenolic byproduct from olive mill wastewater processing improves the redox status in blood and tissues of piglets. Food and Chemical Toxicology : An International Journal Published for the British Industrial Biological Research Association. 2015, 86, 319–327. 

23.  Goutzourelas, N., Stagos, D., Spanidis, Y., Liosi, M., Apostolou, A., Priftis, A., Kouretas, D. Polyphenolic composition of grape stem extracts affects antioxidant activity in endothelial and muscle cells. Molecular Medicine Reports. 2015, 12(4), 58465856.

24.  Priftis, A., Stagos, D., Konstantinopoulos, K., Tsitsimpikou, C., Spandidos, D. A., Tsatsakis, A. M.,  Kouretas, D. Comparison of antioxidant activity between green and roasted coffee beans using molecular methods. Molecular Medicine Reports. 2015, 12(5), 7293–7302.

25.  Spanidis, Y., Goutzourelas, N., Stagos, D., Kolyva, A. S., Gogos, C. A., Bar-Or, D., & Kouretas, D. Assessment of Oxidative Stress in Septic and Obese Patients Using Markers of Oxidation-reduction Potential. In Vivo . 2015, 29(5), 595–600.

26.  Vasilaki, F., Tsitsimpikou, C., Tsarouhas, K., Germanakis, I., Tzardi, M., Kavvalakis, M., Kouretas, D., Tsatsakis, A. M. Cardiotoxicity in rabbits after long-term nandrolone decanoate administration. Toxicology Letters. 2016,  241, 143–151.

27.  Begas E, Tsioutsiouliti A, Kouvaras E, Haroutounian SA, Kasiotis KM, Kouretas D, Asprodini E. Effects of peppermint tea consumption on the activities of CYP1A2, CYP2A6, Xanthine Oxidase, N-acetyltranferase-2 and UDP-glucuronosyltransferases-1A1/1A6 in healthy volunteers. Food Chem Toxicol. 2016 Dec 21;100:80-89. doi: 10.1016/j.fct.2016.12.021

28.  Kerasioti E, Stagos D, Tzimi A, Kouretas D. Increase in antioxidant activity by sheep/goat whey protein through nuclear factor-like 2 (Nrf2) is cell type dependent. Food Chem Toxicol. 2016 Nov;97:47-56. doi: 10.1016/j.fct.2016.08.022. Epub 2016 Aug 20

29.  Kafantaris I , Kotsampasi B, Christodoulou V, Kokka E, Kouka P, Terzopoulou Z, Gerasopoulos K, Stagos D, Mitsagga C, Giavasis I, Makri S, Petrotos K, Kouretas D. Grape pomace improves antioxidant capacity and faecal microflora of lambs. J Anim Physiol Anim Nutr (Berl). 2016 Oct 18. doi: 10.1111/jpn.12569.

30.  Priftis A, Stagos D, Tzioumakis N, Konstantinopoulos K, Patouna A, Papadopoulos GE, Tsatsakis A, Kouretas D. Development and Validation of a Kit to Measure Drink Antioxidant Capacity Using a Novel Colorimeter. Molecules. 2016 Aug 30;21(9). pii: E1154. doi: 10.3390/molecules21091154.

31.  Tsitsimpikou C, Vasilaki F, Tsarouhas K, Fragkiadaki P, Tzardi M, Goutzourelas N, Nepka C, Kalogeraki A, Heretis I, Epitropaki Z, Kouretas D, Tsatsakis AM. Nephrotoxicity in rabbits after long-term nandrolone decanoate administration. Toxicol Lett. 2016 Sep 30;259:21-7. doi: 10.1016/j.toxlet.2016.06.1122.

32.  Georgakouli K, Mpesios A, Kouretas D, Petrotos K, Mitsagga C, Giavasis I, Jamurtas AZ. The Effects of an Olive Fruit Polyphenol-Enriched Yogurt on Body Composition, Blood Redox Status, Physiological and Metabolic Parameters and Yogurt Microflora. Nutrients. 2016 Jun 3;8(6). pii: E344. doi: 10.3390/nu8060344.

33.  Kerasioti E, Stagos D, Georgatzi V, Bregou E, Priftis A, Kafantaris I, Kouretas D. Antioxidant Effects of Sheep Whey Protein on Endothelial Cells. Oxid Med Cell Longev. 2016;2016:6585737. doi: 10.1155/2016/6585737. Epub 2016 Mar 31.

34.  Gerasopoulos K, Stagos D, Krouezas A, Karaveli C, Barda C, Gkika H, Mitsiou D, Petrotos K, Goulas P, Kouretas D. Assessment of Fatty Acid Allocation in Plasma and Tissues in Piglets, Using Feed Supplemented with Byproducts from Processed Olive Mill Wastewater. In Vivo. 2016 May-Jun;30(3):291-301.

35.  Spanidis Y, Mpesios A, Stagos D, Goutzourelas N, Bar-Or D, Karapetsa M, Zakynthinos E, Spandidos DA, Tsatsakis AM, Leon G, Kouretas D. Assessment of the redox status in patients with metabolic syndrome and type 2 diabetes reveals great variations. Exp Ther Med. 2016 Mar;11(3):895-903. Epub 2016 Jan 5.

36.  Spanidis Y, Goutzourelas N, Stagos D, Mpesios A, Priftis A, Bar-Or D, Spandidos DA, Tsatsakis AM, Leon G, Kouretas D. Variations in oxidative stress markers in elite basketball players at the beginning and end of a season. Exp Ther Med. 2016 Jan;11(1):147-153. Epub 2015 Nov 4.

37.  Vardavas AI, Fragkiadaki P, Alegakis AK, Kouretas D, Goutzourelas N, Tsiaoussis J, Tsitsimpikou C, Stivaktakis PD, Carvalho F, Tsatsakis AM. Downgrading the systemic condition of rabbits after long term exposure to cypermethrin and piperonyl butoxide. Life Sci. 2016 Jan 15;145:114-20. doi: 10.1016/j.lfs.2015.12.026. Epub 2015 Dec 12. 

38.  Vasilaki F, Tsitsimpikou C, Tsarouhas K, Germanakis I, Tzardi M, Kavvalakis M, Ozcagli E, Kouretas D, Tsatsakis AM. Cardiotoxicity in rabbits after long-term nandrolone decanoate administration. Toxicol Lett. 2016 Jan 22;241:143-51. doi: 10.1016/j.toxlet.2015.10.026. Epub 2015 Nov 2.

39.  Makri S, Kafantaris I, Stagos D, Chamokeridou T, Petrotos K, Gerasopoulos K, Mpesios A, Goutzourelas N, Kokkas S, Goulas P, Komiotis D, Kouretas D., Novel feed including bioactive compounds from winery wastes improved broilers' redox status in blood and tissues of vital organs., Food and Chemical Toxicology. 2017 Jan 24;102:24-31. doi: 10.1016/j.fct.2017.01.019.

40.  Begas E, Tsioutsiouliti A, Kouvaras E, Haroutounian SA, Kasiotis KM, Kouretas D, Asprodini E., Effects of peppermint tea consumption on the activities of CYP1A2, CYP2A6, Xanthine Oxidase, N-acetyltranferase-2 and UDP-glucuronosyltransferases-1A1/1A6 in healthy volunteers., Food and Chemical Toxicology. 2017 Feb;100:80-89. doi: 10.1016/j.fct.2016.12.021.




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