一、个人简介
赵凤红，副教授，硕士研究生导师，劳动卫生教研室。
二、教育经历
2002-2007年：中国医科大学 预防医学 学士
2007-2010年：中国医科大学 劳动卫生与环境卫生学 硕士
2010-2013年：中国医科大学 劳动卫生与环境卫生学 博士
三、工作经历（包括博士后及出国进修经历）
2013-2018年：中国医科大学 公共卫生学院 劳动卫生教研室 讲师
2018-2019年：美国约翰霍普金斯大学医学院 博士后
2019-至今：中国医科大学 公共卫生学院 劳动卫生教研室 副教授
四、研究方向
职业与环境污染物的毒性机制与防治研究
五、主持课题情况
辽宁省科学技术厅重点研发项目：ANLS介导的神经细胞自噬在低浓度1,2-DCE暴露致神经毒性中的作用及机制研究，2024-2026。
横向合作项目：环卫工人职业健康调查与保护策略研究，2022-2023。
横向合作项目：教师职业健康调查与保护策略研究，2021-2022。
国家自然科学基金：低浓度1,2-二氯乙烷长期暴露的神经毒性及其机制研究，2017-2019。
新教师课题项目：Glu代谢在1,2-二氯乙烷致学习记忆损伤中作用的研究，2016-2018。
六、文章发表情况
1. Qin Y, Huang W, Wang Z, Wang C, Wang C, Zhang M, Wu S, Wang G, Zhao F*. 1,2-Dichloroethane causes anxiety and cognitive dysfunction in mice by disturbing GABA metabolism and inhibiting the cAMP-PKA-CREB signaling pathway. Ecotoxicol Environ Saf. 2024, 279:116464.
2. Wang T, Yang J, Wang G, Zhao F, Jin Y. Factors ameliorate pro-inflammatory microglia polarization through inhibition of reactive astrocytes induced by 2-chloroethanol. Ecotoxicol Environ Saf. 2023, 261:115130.
3. Yang J, Zhang L, Wang T, Zhang J, Li M, Jin X, Tan X, Wang G, Zhao F, Jin Y. Synergistic effects of combined treatment of 1,2-dichloroethane and high-dose ethanol on liver damage in mice and the related mechanisms. Food Chem Toxicol. 2023, 176:113812.
4. Huang W, Wang Z, Wang G, Li K, Jin Y, Zhao F*. Disturbance of glutamate metabolism and inhibition of CaM-CaMKII-CREB signaling pathway in the hippocampus of mice induced by 1,2-dichloroethane exposure. Environ Pollut. 2022, 310:119813.
5. Yang J, Wang T, Jin X, Wang G, Zhao F, Jin Y. Roles of Crosstalk between Astrocytes and Microglia in Triggering Neuroinflammation and Brain Edema Formation in 1,2-Dichloroethane-Intoxicated Mice. Cells. 2021, 10(10):2647.
6. Wang T, Sun Q, Yang J, Wang G, Zhao F, Chen Y, Jin Y. Reactive astrocytes induced by 2-chloroethanol modulate microglia polarization through IL-1β, TNF-α, and iNOS upregulation. Food Chem Toxicol. 2021, 157:112550.
7. Xue Y, Fu Y, Zhao F, Gui G, Li Y, Rivero-Hinojosa S, Liu G, Li Y, Xia S, Eberhart C, Ying M. Frondoside A Inhibits an MYC-Driven Medulloblastoma Model Derived from Human-Induced Pluripotent Stem Cells. Mol Cancer Ther. 2021, 20(6):1199-1209.
8. Zhao F, Wang Z, Liao Y, Wang G, Jin Y. Alterations of NMDA and AMPA receptors and their signaling apparatus in the hippocampus of mouse offspring induced by developmental arsenite exposure. J Toxicol Sci. 2019, 44:777-788.
9. Tang H, Sun Q, Wang T, Liao Y, Wang G, Zhao F, Jin Y. Upregulation of CYP2E1 expression causes oxidative damage induced by 2-chloroethanol in primary cultured rat astrocytes. Neurotoxicology. 2019, 75:233-244.
10. Jin X, Wang T, Liao Y, Guo J, Wang G, Zhao F, Jin Y. Neuroinflammatory Reactions in the Brain of 1,2-DCE-Intoxicated Mice during Brain Edema. Cells. 2019, 8(9):987.
11. Wang T, Jin X, Liao Y, Sun Q, Luo C, Wang G, Zhao F, Jin Y. Association of NF-κB and AP-1 with MMP-9 Overexpression in 2-Chloroethanol Exposed Rat Astrocytes. Cells. 2018, 7(8):96.
12. Wang G, Yuan Y, Gao L, Tan X, Yang G, Zhao F, Jin Y. Disruption of Intracellular ATP Generation and Tight Junction Protein Expression during the Course of Brain Edema Induced by Subacute Poisoning of 1,2-Dichloroethane. Front Neurosci. 2018, 12:12.
13. Jin X, Liao Y, Tan X, Guo J, Wang G, Zhao F, Jin Y. Involvement of the p38 MAPK signaling pathway in overexpression of matrix metalloproteinase-9 during the course of brain edema in 1,2-dichloroethane-intoxicated mice. Neurotoxicology. 2018, 69:296-306.
14. Jin X, Liao Y, Tan X, Wang G, Zhao F, Jin Y. Involvement of CYP2E1 in the Course of Brain Edema Induced by Subacute Poisoning With 1,2-Dichloroethane in Mice. Front Pharmacol. 2018, 9:1317.
15. Zhao F, Liao Y, Tang H, Piao J, Wang G, Jin Y. Effects of developmental arsenite exposure on hippocampal synapse in mouse offspring. Metallomics. 2017, 9:1394-1412.
16. Wang T, Liao Y, Sun Q, Tang H, Wang G, Zhao F, Jin Y. Upregulation of Matrix Metalloproteinase-9 in Primary Cultured Rat Astrocytes Induced by 2-Chloroethanol Via MAPK Signal Pathways. Front Cell Neurosci. 2017, 11:218.
17. Sun Q, Liao Y, Wang T, Tang H, Wang G, Zhao F, Jin Y. 2-Chloroethanol Induced Upregulation of Matrix Metalloproteinase-2 in Primary Cultured Rat Astrocytes Via MAPK Signal Pathways. Front Neurosci. 2017, 10:593.
18. Sun Q, Liao Y, Wang T, Tang H, Wang G, Zhao F, Jin Y. Alteration in mitochondrial function and glutamate metabolism affected by 2-chloroethanol in primary cultured astrocytes. Toxicol In Vitro. 2016, 37:50-60.
19. Yu H, Liao Y, Li T, Cui Y, Wang G, Zhao F, Jin Y. Alterations of Synaptic Proteins in the Hippocampus of Mouse Offspring Induced by Developmental Lead Exposure. Mol Neurobiol. 2016, 53(10):6786-6798.
20. Yu H, Liao Y, Li T, Cui Y, Liao Y, Wang G, Gao L, Zhao F, Jin Y. Effects of lead exposure on D-serine metabolism in the hippocampus of mice at the early developmental stages.Toxicology. 2014, 325:189-99.
21. Lu C, Zhao F, Sun D, Zhong Y, Yu X, Li G, Lv X, Sun G, Jin Y. Comparison of speciated arsenic levels in the liver and brain of mice between arsenate and arsenite exposure at the early life. Environ Toxicol. 2014, 29(7):797-803.
22. Wang Y, Zhao F, Liao Y, Jin Y, Sun G. Effects of arsenite in astrocytes on neuronal signaling transduction. Toxicology. 2013, 303:43-53.
23. Zhao F, Wang Y, Jin Y, Zhong Y, Yu X, Li G, Lv X, Sun G. Effects of exogenous methionine on arsenic burden and NO metabolism in brain of mice exposed to arsenite through drinking water. Environ Toxicol. 2012, 27:700-706.
24. Zhao F, Liao Y, Jin Y, Li G, Lv X, Sun G. Effects of arsenite on glutamate metabolism in primary cultured astrocytes. Toxicol In Vitro. 2012, 26:24-31.
25. Wang Y, Zhao F, Liao Y, Jin Y, Sun G. Arsenic exposure and glutamate-induced gliotransmitter release from astrocytes. Neural Regen Res. 2012, 7(31):2439-45.
26. Wang Y, Zhao F, Jin Y, ZhongY, Xiaoyun Yu, Gexin Li, Xiuqiang Lv, Guifan Sun. Effects of exogenous glutathione on arsenic burden and NO metabolism in brain of mice exposed to arsenite through drinking water. Arch Toxicol. 2011, 85(3):177-84.
七、研究生培养情况
研究生培养：2020年始，共招收12人。
八、教材编写和期刊编委情况
2023年-至今：《工业卫生与职业病》青年编委。
九、学会及其他学术团体任职情况
2024年-至今：中国毒理学会神经毒理专业委会青年委员
2025年-至今：辽宁省防痨协会第九届理事会理事
十、获得奖励及荣誉称号情况
2018年：中国医科大学中青年教师基本功讲课比赛三等奖
2020年：中国医科大学微课比赛优秀奖
2024年：中国医科大学优秀研究生指导教师
