李鹤然，女，副教授，硕士生导师，辽宁省百千万人才工程，辽宁省优秀毕业生，沈阳市拔尖人才，中国医科大学青年骨干人才，中国医科大学青年英才计划入选者，中国医科大学五四青年奖章获得者。本科毕业于吉林大学化学学院，沈阳药科大学博士，中国医科大学药理学博士后。具有化学和药学背景，主要研究方向为智能药物递送系统构建及跨越生物屏障给药。主持或参与国家自然科学基金、科技部重大新药创制等国家和省部级科研项目10项，获批专利3项，参与完成的3个药品一致性评价。近五年来以第一作者或通讯作者在ACS Nano等期刊发表SCI论文28篇，总影响因子220分以上，其中中科院一区论文13篇。任Asian J Pharm Sci、Acta Pharm Sin B、Acta Materia Medica、药学学报、沈阳药科大学学报等期刊青年编委，是Acta Biomater、Expert Opin Drug Del、Colloid surface B、Drug Deliv、Int J Nanomed、Mat Sci Eng C、ACS Appl Mat Int、AAPS PharmSciTech、Acta Pharm Sin B、Micropor Mesopor Mat等期刊审稿人。E-mail：liheranmm@163.com
代表论文（10篇）：
1. Chiral Nanosilica Drug Delivery Systems Stereoselectively Interacted with the Intestinal Mucosa to Improve the Oral Adsorption of Insoluble Drugs. Xuchun Chen, Ying Cheng, Qi Pan, Lan Wu, Xinyao Hao, Zhiye Bao, Xitan Li, Mingshi Yang, Qiuhua Luo*, Heran Li*.ACS Nano. 2023.10818. IF 18.027.中科院一区
2. Synthesis, structural properties, applications and biosafety of chiral mesoporous silica nanostructures.Kaijun Gou,Yumei Wang,Linlin Xie,Xianmou Guo,Yingyu Guo,Jia Ke,Lulu Wu,Sanming Li*,Heran Li*.Chemical Engineering Journal.2021, 127862. IF: 16.744,中科院一区
3. Chiral mesoporous silica nano-screws as an efficient biomimetic oral drug delivery platform through multiple topological mechanisms.Yumei Wang, Jia Ke, Xianmou Guo, Kaijun Gou, Zhentao Sang, Yanbu Wang, Yan Bian, Sanming Li*,Heran Li*.Acta Pharmaceutica Sinica B. 2021 08 014. IF: 14.91,中科院一区
4. Carboxyl-functionalized mesoporous silica nanoparticles for the controlled delivery of poorly water-soluble non-steroidal anti-inflammatory drugs.Kaijun Gou, Yumei Wang, Xianmou Guo, Yan Bian, Haiqing Zhao, Yingyu Guo, Yue Pang, Linlin Xie, Sanming Li*,Heran Li*. Acta Biomaterialia. 134 (2021) 576-592. IF:10.533,中科院一区
5. Advances in regulating physicochemical properties of mesoporous silica nanocarriers to overcome biological barriers. Yumei Wang, Kaijun Gou, Xianmou Guo, Jia Ke, Sanming Li*,Heran Li*. Acta Biomaterialia. 2021,123, 72-92. IF: 10.533,中科院一区
6. pH/H2O2-dual responsive chiral mesoporous silica nanorods coated with biocompatible active targeting ligand for cancer therapy Yumei Wang, Jing Wang, Kaijun Gou, Wei Kang, Xianmou Guo, Keyu Zhu, Sanming Li,*and Heran Li*. ACS applied Material& interfaces.2021 13 (30), 35397-35409. IF:10.383,中科院一区
7. Mesoporous silica nanoparticles with chiral pattern topological structure function as “antiskid tires” on the intestinal mucosa to facilitate oral drugs delivery. Wei Xin , Lin Wang , Jiahui Lin , Yanbu Wang , Qi pan , Yang Han , Zhiye Bao , Shun Zong , Ying Cheng , Xuchun Chen , Lin Zhao , Heran Li. Asian Journal of Pharmaceutical Sciences..2022, 100795. IF: 9.273,中科院一区
8. Biomimetic aminoated mesoporous silica xerogel exhibiting chiral surface topology for delivery insoluble drug with multiple-controlled manners and improved oral adsorption. Xianmou Guo, Kaijun Gou, Yang Han, Qi Pan, Yuxin Wang, Shun Zong, Jiexin Song, Xuchun Chen*, Heran Li*. Materials & Design. 2022. 223.111157. IF:9.417,中科院一区.
9. Multi-functional extracellular vesicles: Potentials in cancer immunotherapy. Ling Zhang, Mengchi Sun, Zhonggui He, Jin Sun, Heran Li*, Qiuhua Luo*. Cancer Letters. 2022. 551. 215934. IF:9.756,中科院一区.
10. Advances and prospects of Bletilla striata polysaccharide as promising multifunctional biomedical materials. Kaijun Gou, Yuan Li, Yan Qu*, Heran Li*, Rui Zeng*. Materials & Design. 2022. 223. 111198. IF:9.417,中科院一区.
