硕士研究生导师
药物分析学-宋洋


一、个人简介

宋洋,博士,教授,中共党员,硕士研究生导师。Email:songyanglhyb1998@163.com

二、教育经历

(1) 2008-08至2012-10,沈阳药科大学,药物分析学,博士

(2) 2004-08至2008-07,沈阳药科大学,药学理科基地班,学士

三、博士后工作经历

(1) 2018-08至2021-10,中国医科大学,药理学,导师魏敏杰教授

四、科研与学术工作经历

(1) 2022-12至 今,中国医科大学,药学院,教授

(2) 2016-12至2022-12,中国医科大学,药学院,副教授

(3) 2018-01至2019-01,美国爱荷华大学,内科学,副研究员

(4) 2012-07至2016-12,中国医科大学,药学院,讲师

五、研究方向

(1) 中药质量控制

(2)中药药代动力学

(3)中药药效物质基础

六、主持课题情况

(1)国家自然科学基金委员会,青年科学基金项目, 81303195,无梗五加果抗血小板和抗血栓药效物质基础及作用机制研究, 2014-01至2016-12,23万元。

(2) 辽宁省科技厅,自然科学基金项目, 2020-MS-171,金丝马尾连预防结肠癌的药效物质及其对TLR4/MyD88/NF-κB p65通路的调控作用研究, 2020-05至2023-04, 5万元。

七、发表论文情况

(1)Kefei Wang, Kun Jiang, Xiaoyi Wei, Yulan Li, Tiejie Wang,Yang Song*. Physiologically Based Pharmacokinetic Models Are Effective Support for Pediatric Drug Development. AAPS PharmSciTech, 2021, 22(6). doi: 10.1208/s12249-021-02076-w. (SCI收录,IF=3.24)

(2)Yang Song , Kefei Wang, Xiaoyi Wei, Tongyuan Wei , Tianhao Xiao , Minjie Wei*. Pharmacokinetics, tissue distribution and plasma protein binding rate of palmatine following intragastric and intravenous administration in rats using liquid chromatography tandem mass spectrometry. J Pharm Biomed Anal, 2021, 203:114226. doi: 10.1016/j.jpba.2021.114226. (SCI收录,IF=3.935)

(3)Yang Song, Xue-Song Feng*. Sample Preparation and Analytical Methods for Steroid Hormones in Environmental and Food Samples: An Update Since 2012. Crit Rev Anal Chem, 2021, 1-19. doi: 10.1080/10408347.2021.1936446.(SCI收录,IF=5.686)

(4)Yang Song, Yuan Zhang, Xiao-Yi Duan, Dong-Wei Cui, Xin Qiu, Yu Bian, Ke-Fei Wang, and Xue-Song Feng*. Pharmacokinetics and Tissue Distribution of Anwuligan in Rats after Intravenous and Intragastric Administration by Liquid Chromatography-Mass Spectrometry. Molecules, 2019, 25(1). doi: 10.3390/molecules25010039.(SCI收录,IF=3.060)

(5)Yang Song, Yu Zhou, Xiaoting Yan, Jingbo Bi, Xin Qiu, Yu Bian, Kefei Wang, Yuan Zhang and Xuesong Feng*. Pharmacokinetics and Tissue Distribution of Alnustone in Rats after Intravenous Administration by Liquid Chromatography-Mass Spectrometry. Molecules, 2019, 24(17). doi: 10.3390/molecules24173183.(SCI收录,IF=3.060)

(6)Yang Song, Yuan Zhang, Weipeng Zhang, Baozhen Zhang, Kefei Wang and Xuesong Feng*. Interaction Effects between Doxorubicin and Hernandezine on the Pharmacokinetics by Liquid Chromatography Coupled with Mass Spectrometry. Molecules, 2019, 24(19). doi: 10.3390/molecules24193622.(SCI收录,IF=3.060)

(7)Yang Song, Zhibin Wang, Baozhen Zhang, Weipeng Zhang, Yujia Zhang, Chunjuan Yang, Fanhao Meng*, Xuesong Feng*. Determination of a novel anticancer AMPK activator Hernandezine in rat plasma and tissues with a validated UHPLC-MS/MS method: application to pharmacokinetics and tissue distribution study. Journal of pharmaceutical and biomedical analysis, 2017, 141, 132-139.(SCI收录,IF=2.831)

(8)Yang Song, Chunjuan Yang, Zhibin Wang, Nan Zhao, Xuesong Feng, Fanhao Meng*. Chemical constituents of Eleutherococcus sessiliflorus extract and its sedative-hypnotic effect. Natural Product Research, 2017, Dio: 10.1080/14786419.2016.1272106.(SCI收录,IF=1.828)

(9)Yang Song, Zhibin Wang, Xuesong Feng, et al. Simultaneous determination and pharmacokinetics of four triterpenoids by ultra high performance liquid chromatography with tandem mass spectrometry after the oral administration of Acanthopanax sessiliflorus (Rupr. et Maxim) Seem extract. Journal of Separation Science, 2016, 00, 1-9.(SCI收录,IF=2.557)

(10)Yang Song, Ying Deng, Danxue Huang, et al. LC–MS/MS determination and pharmacokinetic study of four lignan components in rat plasma after oral administration of Acanthopanax sessiliflorus extract. Journal of Ethnopharmacology, 2012, 141: 957-963.(SCI收录,IF=2.981)

八、教材编写情况

(1)《药物分析》,上海科学技术出版社,副主编,2017年1月

九、人才称号

(1) 沈阳市高层次人才人选-拔尖人才(2018年度第七批)

十、学会及其他学术团体任职情况

2019年被聘为辽宁省药学会第九届药物分析专业委员会委员