个人简介：

郭启强，教授，博士生导师，现任中国医科大学国际教育学院副院长、生命科学学院分子细胞生物学教研室主任。兼任中华医学会医学细胞生物学分会青年学组副组长。

长期聚焦细胞应激与细胞稳态维系在肿瘤及衰老相关疾病中的调控机制。代表性成果以第一或通讯作者在Nature Communications、PNAS、Science Advances、EMBO J等国际权威期刊发表。主持国家科技重大专项子课题、国家自然科学基金等国家级、省市级项目10余项。

联系方式：qqguo@cmu.edu.cn

代表性研究成果：

1.Xie XC^#,*, Guo Y^#, Guo R^#, Li YZ^#, Wang SS, Jiang XY, Hao S, Zhang Y, Li YH, Liu XY, Wu XX, Zhang XY, Guo WD, Feng YL, Li JB, Liu C, Wang L, Li ZH, Teng WP*, Shan ZY*, Cao L*,Guo QQ*, Mitophagy mitigates mitochondrial DNA-induced activation of cGAS-STING in autoimmune thyroiditis,Nat Commun, 2026, https://doi.org/ 10.1038/s41467-026-76047-9.

2.Guo QQ^#,*, Wang SS^#, Jiang XY^#, Xie XC^#, Zou Y, Liu JW, Guo Y, Li YH, Liu XY, Hao S, Zhang XY, Wu XX, Lu SM, Xu HD, Guo WD, Feng YL, Wang CG, Zhang SP, Li JB, Liu C, Song XY*, Finkel T*, Cao L*, Mitochondrial ROS triggers mitophagy through activating the DNA damage response signaling pathway,Proc Natl Acad Sci U S A, 2025 Oct 7;122(40): e2502841122.

3.Jiang XY^#,Guo QQ^#,*, Wang SS^#, Guo R^#, Zou Y, Liu JW, Feng YL, Guo Y, Li YH, Liu XY, Zhang XY, Hao S, Wu XX, Li MH, Liu A, Li CL, Guo WD, Xu HD, Song XY*, Finkel T*, Cao L*, DNA damage response pathway regulates Nrf2 in response to oxidative stress,Sci Adv, 2025 Jul 25;11(30): eadu9555.

4.Guo QQ, Wang SS, Zhang SS, Xu HD, Li XM, Guan Y, Yi F, Zhou TT, Jiang B, Bai N, Ma MT, Wang Z, Feng YL, Guo WD, Wu X, Zhao GF, Fan GJ, Zhang SP, Wang CG, Cao LY, O'Rourke BP, Liu SH, Wang PY, Han S*, Song XY*, Cao L*, ATM-CHK2-Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress,EMBO J, 2020 Mar 18: e103111.