导师简介

温莉莉，副教授，硕士生导师。获山东中医药大学医学学士学位，硕博连读于中国医科大学 人体解剖与组织胚胎学专业，具有生物学专业博士后研究背景，主持和参与科技部研发计划项目1项，国家自然科学基金2项，中国博士后自然科学基金面上项目1项，辽宁省自然科学基金面上项目1项，获省市级奖2项，发表SCI论文16篇。

研究方向

生物材料、组织修复与再生、创伤应激、肿瘤治疗等。

科研成果

1. Wen LL, Yu TH, Ma YZ, Mao XY, Ao TR, Javed R, Ten H, Matsuno A, Ao Q. Sequential expression of miR-221-3p and miR-338-3p in Schwann cells as a therapeutic strategy to promote nerve regeneration and functional recovery. Neural Regen Res. 2023 18(3):671-682.

2. Yu T, Wen L, He J, Xu Y, Li T, Wang W, Ma Y, Ahmad MA, Tian X, Fan J, Wang X, Hagiwara H, Ao Q. Fabrication and evaluation of an optimized acellular nerve allograft with multiple axial channels. Acta Biomater. 2020 Aug 7: S1742-7061(20)30456-6.

3. Lili Wen, Fan Han, Yuxiu Shi. Changes in the Glucocorticoid Receptor and Ca2+/Calreticulin-Dependent Signalling Pathway in the Media Prefrontal Cortex of Rats with Post-traumatic Stress Disorder. J Mol Neurosci. 2015 May,56(1):24-34.

4. Lili Wen, Fang Han, BingXiao, Yuxiu Shi. PERK signalling pathway mediates single prolonged stress-induced dysfunction of medial prefrontal cortex neurons. apoptosis.2017(22):753-768.

5. Lili Wen, Xiaoyan Li, Fang Han, Yuxiu Shi. Role of the endoplasmic reticulum pathway in medial prefrontal cortex in posttramtic stress disorder model rats. J Mol Neurosci.2016 Aug;59(4):471-82.

6. Cong M, Wen L, Han F, Xu Y, Shi Y. Alterations in cyclin D1 and cyclin dependent kinase 4 expression in the amygdalae of posttraumatic stress disorder rats. Mol Med Rep. 2017; 16(6):8351-8358.

7. Yu B, Wen L, Xiao B, Han F, Shi Y. Single Prolonged Stress induces ATF6 alpha-dependent Endoplasmic reticulum stress and the apoptotic process in medial Frontal Cortex neurons. BMC Neurosci. 2014; 15:115.

8. Han D, Han F, Shi Y, Zheng S, Wen L. Mechanisms of Memory Impairment Induced by Orexin-A via Orexin 1 and Orexin 2 Receptors in Post-traumatic Stress Disorder Rats.Neuroscience. 2020 Apr 15;432:126-136.