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我院科研成果简报

根据2020年度期刊引用报告,我院自2020年至今以中国医科大学为第一通讯作者单位发表的SCI收录论文中科院Q1区26篇、Q2区论文共计47篇,汇总情况如下。

(一)中科院Q1区论文26篇(15篇IF>8,8篇IF>10)

序号

论文名称

第一作者

通讯作者

科室

中科院

分区

期刊名称

最新影响因子

1

Cerebrospinal fluid influx drives acute ischemic tissue swelling

Mestre H/杜婷

Nedergaard M

药物分析学教研室

Q1

Science

47.728

2

Long noncoding RNA ZFAS1 promoting small nucleolar RNA-mediated 2’-O-methylation via NOP58 recruitment in colorectal cancer

吴慧哲/秦文艳

魏敏杰/张睿

药理学教研室

Q1

Molecular Cancer

27.401

3

HLA-A2.1-restricted ECM1-derived epitope LA through DC cross-activation priming CD8+ T and NK cells: a novel therapeutic tumour vaccine

于兆进/刘雯思/何英

魏敏杰/李剑平/张睿

药理学教研室

Q1

J Hematol Oncol

17.388

4

MCOLN1/TRPML1 finely controls oncogenic autophagyin cancer by mediating zinc influx

齐剑崧/邢燕红/刘宇程/王萌萌

王午阳/郭凤

药物毒理学教研室

Q1

autophagy

16.016

5

Synthesis, structural properties, applications and biosafety of chiral mesoporous silica nanostructures

苟恺军/王玉美

李鹤然/李三鸣

药物分析学教研室

Q1

Chemical Engineering Journal

13.273

6

Pan-Cancer Analysis of NLRP3 Inflammasome with Potential Implications in Prognosis and Immunotherapy in Human Cancer.

鞠铭伊

赵琳/魏敏杰

药理学教研室

Q1

Briefings in bioinformatics

11.622

7

Progress in the pretreatment and analysis of

N-nitrosamines: an update since 2010

边煜

冯雪松

药物分析学教研室

Q1

Critical Reviews in Food Science and Nutrition

11.176

8

LncRNA CBR3-AS1 regulates of breast cancer drug sensitivity as a competing endogenous RNA through the JNK1/MEK4mediated MAPK signal pathway

张明/王岩

赵琳/魏敏杰

药理学教研室

Q1

Journal of Experimental & Clinical Cancer Research.

11.161

9

LNC942 promoting METTL14-mediated m6A methylation in breast cancer cell proliferation and progression

孙桐

吴慧哲/魏敏杰

药理学教研室

Q1

Oncogene

9.867

10

NF-κB-activated SPRY4-IT1 promotes cancer cell metastasis by down-regulating TCEB1 mRNA via Staufen1-mediated mRNA decay

赵琳/江龙洋

魏敏杰

药理学教研室

Q1

oncogene

9.867

11

Direct Measurement of Cerebrospinal Fluid Production in Mice.

刘国军

杜婷/ Nedergaard M

药物分析学教研室

Q1

Cell Reports

9.423

12

Co-delivery of etoposide and cisplatin in dual-drug loaded nanoparticles synergistically improves chemoradiotherapy in non-small cell lung cancer models

张懋璠

Wang Andrew

药剂学教研室

Q1

Acta Biomaterialia

8.947

13

Advances in regulating physicochemical properties of mesoporous silica nanocarriers to overcome biological barriers.

王玉美/苟恺军

李鹤然/李三鸣

药物分析学教研室

Q1

Acta Biomaterialia

8.947

14

Honokiol inhibits colorectal cancer by targeting TMEM16A Ca2+-activated Cl- channels

王天宇

肖庆桓

离子通道药理研究室

Q1

British Journal of Pharmacology

8.739

15

Silencing KIF18B enhances radiosensitivity: identification of a promising therapeutic target in sarcoma

刘雯思/于兆进

魏敏杰/张敬东

药理学教研室

Q1

EBioMedicine

8.143

16

Progress in pretreatment and analysis of organic Acids: An update since 2010

邱鑫

冯雪松

药物分析学教研室

Q1

Food Chemistry

7.514

17

2-((1-Phenyl-1H-1,2,3-triazol-4-yl)methyl)-2-azabicyclo[3.2.1]octan-3-one derivatives: Simplification and modification of aconitine scaffold for the discovery of novel anticancer agents

张毅/张廷剑

孟繁浩

药物化学教研室

Q1

European Journal of Medicinal Chemistry

6.514

18

Design, synthesis, and in vitro and in vivo

anti-angiogenesis study of a novel vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitor based on 1,2,3-triazole scaffold

王德普/刘凯利

孟繁浩

药物化学教研室

Q1

European Journal of Medicinal Chemistry

6.514

19

The role of internal and external stimuli in the rational design of skin-specific drug delivery systems

陈阳

陈阳

药剂学教研室

Q1

International Journal of Pharmaceutics

5.875

20

Design, synthesis and biological evaluation of novel (E)-N-phenyl-4-(pyridine-acylhydrazone) benzamide derivatives as potential antitumor agents for the treatment of multiple myeloma (MM)

李馨阳/李帅

孟繁浩

药物化学教研室

Q1

Bioorganic Chemistry

5.275

21

Design, synthesis and biological evaluation of erythrina derivatives bearing a 1,2,3-triazole moiety as PARP-1 inhibitors

李帅

孟繁浩

药物化学教研室

Q1

Bioorganic Chemistry

5.275

22

Design, synthesis and biological evaluation of homoerythrina alkaloid derivatives bearing a triazole moiety as PARP-1 inhibitors and as potential antitumor drugs.

李帅

孟繁浩

药物化学教研室

Q1

Bioorganic Chemistry

5.275

23

Novel 4,5-dihydrospiro[benzo[c]azepine-1,1'-cyclohexan]-3(2H)-one derivatives as PARP-1 inhibitors: Design, synthesis and biological evaluation

李帅

孟繁浩

药物化学教研室

Q1

Bioorganic chemistry

5.275

24

NADPH-Cytochrome P450 Reductase Ccr1 Is a Target of Tamoxifen and Participates in Its Antifungal Activity via Regulating Cell Wall Integrity in Fission Yeast.

刘倩楠/郭晓旭

房月/姚凡

微生物与生化药学教研室

Q1

Antimicrobial agents and chemotherapy

5.191

25

A review of pretreatment and analysis of macrolides in food (Update Since 2010)

胡聪

冯雪松

药物分析学教研室

Q1

Journal of Chromatography A

4.759

26

Pretreatment and determination methods for benzimidazoles: An update since 2005

陈兰

冯雪松

药物分析学教研室

Q1

Journal of Chromatography A

4.759

(二)中科院Q2区论文47篇(9篇IF>8,5篇IF>10)

序号

论文名称

第一作者

通讯作者

科室

中科院分区

期刊名称

最新影响因子

1

TMEM16A Ca2+-activated channel inhibition ameliorates acute pancreatitis via the IP3R/Ca2+/NFjB/IL-6 signaling pathway

王清华/白立川

肖庆桓

离子通道药理研究室

Q2

Journal of Advanced Research

10.479

2

Ca2+-activated Cl- channel TMEM16A inhibition by cholesterol promotes angiogenesis in endothelial cells

马可

肖庆桓

离子通道药理研究室

Q2

Journal of Advanced Research

10.479

3

Development of a novel thymidylate synthase (TS) inhibitor capable of up-regulating P53 expression and inhibit angiogenesis in NSCLC

李馨阳

孟繁浩

药物化学教研室

Q2

Journal of Advanced Research

10.479

4

Activation of TMEM16A Ca2+-activated Cl- channels by ROCK1/moesin promotes breast cancer metastasis

雒舒雅

肖庆桓

离子通道药理研究室

Q2

Journal of Advanced research

10.479

5

The diverse roles of TMEM16A Ca2+-activated

Cl− channels in inflammation

白伟良

肖庆桓

离子通道药理研究室

Q2

Journal of Advanced research

10.479

6

Progress in Pretreatment and Analysis of Fatty Acids in Foods: An Update since 2012

刘晓敏

雪松

药物分析学教研室

Q2

Separation and Purification Reviews

9.636

7

Progress in the Pretreatment and Analysis of Flavonoids: An Update since 2013

边煜

冯雪松

药物分析学教研室

Q2

Separation and Purification Reviews

9.636

8

LNC473 regulating APAF1 IRES-dependent translation via competitive sponging miR574 and miR15b: Implications in colorectal cancer

吴慧哲/胡晓云

魏敏杰/张睿

药理学教研室

Q2

Molecular

Therapy-Nucleic Acids

8.886

9

Nuciferine modulates the gut microbiota and prevents obesity in high-fat diet-fed rats

王宇

魏敏杰/刘明妍

药理学教研室

Q2

Experimental Molecular Medicine

8.718

10

Resveratrol protects the integrity of alveolar epithelial barrier via SIRT1/PTEN/p-Akt pathway in methamphetamine-induced chronic lung injury

王鑫

王韵

临床药理教研室

Q2

Cell Proliferation

6.831

11

Peptide-based therapeutic cancer vaccine: Current trends in clinical application

刘雯思

李剑平/于兆进

药理学教研室

Q2

Cell Prolif

6.831

12

SNORA72 Activates the Notch1/c-Myc Pathway to Promote Stemness Transformation of Ovarian Cancer Cells

张丽雯/马荣

何苗/魏敏杰

药理学教研室

Q2

Frontiers in Cell and Developmental Biology

6.684

13

Integrative analysis of DNA methylation and gene expression to determine specific diagnostic biomarkers and prognostic biomarkers of breast cancer

张明

赵琳/魏敏杰/高华

药理学教研室

Q2

Frontiers in Cell and Developmental Biology

6.684

14

Overexpression of PTPRN Promotes Metastasis of Lung Adenocarcinoma and Suppresses NK cells Cytotoxicity

宋昕樾/焦雪

魏敏杰/赵琳

药理学教研室

Q2

Frontiers in Cell and Developmental Biology

6.684

15

Integrated analysis reveals the alterations

that LMNA interacts with euchromatin in LMNA

mutation-associated dilated cardiomyopathy

张晓琳

封瑞

药物毒理学教研室

Q2

Clinical Epigenetics

6.551

16

TBHQ-Overview of Multiple Mechanisms against Oxidative Stress for Attenuating

Methamphetamine-Induced Neurotoxicity

赵元玲

王韵

临床药理学教研室

Q2

Oxidative Medicine and Cellular Longevity

6.543

17

Progress in Pretreatment and Analysis of Cephalosporins: An Update Since 2005

段晓怡

冯雪松

药物分析学教研室

Q2

Critical Reviews in Analytical Chemistry

6.535

18

Sample Preparation and Analytical Methods for Steroid Hormones in Environmental and Food Samples: An Update Since 2012

宋洋

冯雪松

药物分析学教研室

Q2

Critical Reviews in Analytical Chemistry

6.535

19

Technical Overview of Orbitrap High Resolution Mass Spectrometry and Its Application to the Detection of Small Molecules in Food (Update Since 2012)

闫晓婷

冯雪松

药物分析学教研室

Q2

Critical Reviews in Analytical Chemistry

6.535

20

Progress in Pretreatment and Analytical Methods of Coumarins: An Update since 2012-A Review

崔东伟

冯雪松

药物分析学教研室

Q2

Critical Reviews in Analytical Chemistry

6.535

21

Cannabinoids: recent updates on public perception, adverse reactions, pharmacokinetics, pretreatment methods and their analysis methods

李洁

冯雪松

药物分析学教研室

Q2

Critical Reviews in Analytical Chemistry

6.535

22

An Overview of Pretreatment and Analysis of Nucleotides in Different Samples (Update since 2010).

康玮琪

冯雪松

药物分析学教研室

Q2

Critical Reviews in Analytical Chemistry

6.535

23

Puerarin improves the bone micro-environment to inhibit OVX-induced osteoporosis via modulating SCFAs released by the gut microbiota and repairing intestinal mucosal integrity

李博

魏敏杰

药理学教研室

Q2

Biomedicine & Pharmacotherapy

6.529

24

Hypoxia-mediated cancer stem cell resistance and targeted therapy

孙晓雨

魏敏杰

药理学教研室

Q2

Biomedicine & Pharmacotherapy

6.529

25

Exosome loaded genipin crosslinked hydrogel facilitates full thickness cutaneous wound healing in rat animal model

李琦君

魏敏杰/于兆进

药理学教研室

Q2

Drug Delivery

6.419

26

Facile synthesis of PEI-based crystalline templated mesoporous silica with molecular chirality for improved oral delivery of the poorly water-soluble drug.

辛蔚/王玉美

李鹤然

药物分析学教研室

Q2

Drug Delivery

6.419

27

Superiority of L-tartaric Acid Modified Chiral Mesoporous Silica Nanoparticle as a Drug Carrier: Structure, Wettability, Degradation, Bio-Adhesion and Biocompatibility

胡贝贝

李鹤然

药物分析学教研室

Q2

International Journal of Nanomedicine

6.4

28

Biomimetic synthesis and evaluation of interconnected bimodal mesostructured MSF@poly(ethyleneimine)s for improved drug loading and oral adsorption of the poorly water-soluble drug, ibuprofen

辛蔚

李鹤然

药物分析学教研室

Q2

International Journal of Nanomedicine

6.4

29

M6A RNA Methylation Regulators Impact Prognosis and Tumor Microenvironment in Renal Papillary Cell Carcinoma

陈连泽/胡宝慧

赵琳/魏敏杰

药理学教研室

Q2

Frontiers in Oncology

6.244

30

Recent progress on MHC-I epitope prediction in tumor immunotherapy

王香懿/于兆进

魏敏杰/易东旭

药理学教研室

Q2

American Journal of Cancer Research

6.166

31

Bacterially Derived Tryptamine Increases Mucus Release by Activating a Host Receptor in a Mouse Model of Inflammatory Bowel Disease

Bhattarai, Y/司杰

Kashyap, PC/

沙磊

神经内分泌研究室

Q2

iScience

5.458

32

Synthesis and characterization of core-shell mesoporous silica nanoparticles with various shell thickness as indomethacin carriers: In vitro and in vivo evaluation

柯佳

李鹤然/李三鸣

药物分析学教研室

Q2

Microporous and Mesoporous Materials

5.455

33

mTOR-autophagy promotes pulmonary senescence through IMP1 in chronic toxicity of methamphetamine

朱美嘉/刘冰阳

王韵

临床药理学教研室

Q2

Journal of Cellular and Molecular Medicine

5.31

34

LncRNA HOTTIP facilitates the stemness of breast cancer via regulation of miR-148a-3p/WNT1 pathway

韩丽

魏敏杰/何苗

药理学教研室

Q2

Journal of Cellular and Molecular Medicine

5.31

35

Expression signature of six-snoRNA serves as novel non-invasive biomarker for diagnosis and prognosis prediction of renal clear cell carcinoma.

赵燕云/颜媛媛

魏敏杰/刘明妍/何苗

药理学教研室

Q2

Journal of Cellular and Molecular Medicine

5.31

36

A five-mRNA signature associated with

post-translational modifications can better predict recurrence and survival in cervical cancer.

鞠铭伊/齐傲霜

赵琳

药理学教研室

Q2

Journal of Cellular and Molecular Medicine

5.31

37

Integrated microenvironment-associated genomic profiles identify LRRC15 mediating recurrent glioblastoma-associated macrophages infiltration

汤海潮

魏敏杰/于兆进

药理学教研室

Q2

J Cell Mol Med

5.31

38

Gut Microbiota Mediates the Preventive Effects of Dietary Capsaicin Against Depression-Like Behavior Induced by Lipopolysaccharide in Mice.

夏靖/谷莉

张东方

中药生药学教研室

Q2

Frontiers in Cellular and Infection Microbiology

5.293

39

Dual response to pH and chiral microenvironments for the release of a flurbiprofen-loaded chira

self-assembled mesoporous silica drug delivery system

吴路路/苟恺军

李鹤然

药物分析学教研室

Q2

Colloids and Surfaces B-Biointerfaces

5.268

40

The changes of serum zinc, copper, and selenium levels in epileptic patients: a systematic review and meta-analysis.

贾婉莹/宋洋

郭凤

药物毒理学教研室

Q2

Expert Review of Clinical Pharmacology

5.045

41

Mussel-Inspired Polydopamine Coating Enhances the

Intracutaneous Drug Delivery from Nanostructured Lipid Carriers Dependently on a Follicular Pathway

陈阳

陈阳

药剂学教研室

Q2

Molecular Pharmaceutics

4.939

42

Analysis of immune subtypes based on immunogenomic profiling identifies prognostic signature for cutaneous melanoma

胡宝慧/卫倩

赵琳/何苗

药理学教研室

Q2

International Immunopharmacology

4.932

43

Identification of the prognostic value of immune gene signature and infiltrating immune cells for esophageal cancer patients.

王琳

赵琳/魏敏杰

药理学教研室

Q2

International Immunopharmacology

4.932

44

Integrated analysis of mRNA and microRNA

expression profiles reveals differential

transcriptome signature in ischaemic and dilated

cardiomyopathy induced heart failure

邵秀丽

封瑞

药物毒理学教研室

Q2

Epigenetics

4.528

45

Prodrug-type antisense oligonucleotides with enhanced nuclease stability and anti-tumour effects

康玮琪

冯雪松

药物分析学教研室

Q2

European journal of pharmaceutical sciences

4.384

46

The LQT-associated calmodulin mutant E141G induces disturbed Ca2+-dependent binding and a flickering gating mode of the CaV1.2 channel

苏敬阳

郝丽英/高青华

药物毒理学教研室

Q2

American Journal of Physiology-Cell Physiology

4.249

47

Identification of the anti-breast cancer targets of triterpenoids in Liquidambaris Fructus and the hints for its traditional applications

钱平

张东方

中药生药学教研室

Q2

BMC Complementary Medicine and Therapies

3.659

恭喜取得优异科研业绩的老师和同学!期待全院师生继续秉承“团结、进取、求实、创新”的工作精神,埋头苦干,再接再厉,争取取得更好的科研成果,热烈庆祝中国共产党成立100周年,为中国医科大学建校90周年献礼!

 

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                                                                                                2021年7月1日